GGT5

Across TCGA patient cohorts, GGT5 protein abundance is significantly associated with the RNA expression of many other genes, with 20,237 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GGT5-associated genes across cancer lineages are FBLN5, TMEM119, and C7. Each is linked with GGT5 in more than 9 cancer types. Because this analysis shows association rather than direction, both GGT5-to-partner and partner-to-GGT5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GGT5 versus FBLN5 in CCRCC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GGT5→partner) and Y-score (partner→GGT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	FBLN5 →	+1.523	+0.594	<.001	<.001	3	10
OV	TMEM119 →	+1.308	+0.418	<.001	<.001	3	10
OV	C7 →	+2.916	+0.630	<.001	<.001	3	9
CCRCC	PDGFRA →	+1.647	+0.714	<.001	<.001	3	9
BRCA	ABCA8 →	+1.066	+0.453	<.001	<.001	3	9
BRCA	ABCA9 →	+0.893	+0.457	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,237 associations by consensus.

GGT5 vs FBLN5 — CCRCC

Explore this scatter interactively →