GGT5

Across TCGA cell cohorts, GGT5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,049 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GGT5-associated GO terms across cancer lineages are Golgi to plasma membrane transport, Vesicle-mediated transport to the plasma membrane, and Fusion of virus membrane with host plasma membrane. Each is linked with GGT5 in more than 6 cancer types. Because this analysis shows association rather than direction, both GGT5-to-partner and partner-to-GGT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi to plasma membrane transport grouped by GGT5-low versus GGT5-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GGT5→partner) and Y-score (partner→GGT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Golgi to plasma membrane transport →	+0.061	+1.503	.001	.004	3	7
LIVER	Vesicle-mediated transport to the plasma membrane →	+0.073	+1.966	<.001	<.001	3	6
BLOOD_Leukemia	Fusion of virus membrane with host plasma membrane →	+1.089	+1.361	<.001	<.001	3	6
BLOOD_Leukemia	Membrane fusion involved in viral entry into host cell →	+1.089	+1.361	<.001	<.001	3	6
BLOOD_Myeloma	Regulation of syncytium formation by plasma membrane fusion →	+0.052	+0.054	.001	.005	3	5
LIVER	Glycosphingolipid catabolic process →	+0.143	+1.978	.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,049 associations by consensus.

Golgi to plasma membrane transport by GGT5 expression — PANCREAS

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