GGN

Across TCGA cell cohorts, GGN RNA expression is significantly associated with the go_rna of many other GO terms, with 3,551 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GGN-associated GO terms across cancer lineages are Lipoprotein localization, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Lipoprotein transport. Each is linked with GGN in more than 14 cancer types. Because this analysis shows association rather than direction, both GGN-to-partner and partner-to-GGN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipoprotein localization grouped by GGN-low versus GGN-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GGN→partner) and Y-score (partner→GGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Lipoprotein localization →	+0.137	+0.994	<.001	.004	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.121	+0.305	<.001	<.001	3	13
BREAST	Lipoprotein transport →	+0.130	+0.449	<.001	<.001	2	13
LARGE_INTESTINE	Calcium-independent cell-matrix adhesion →	+0.254	+0.542	<.001	<.001	3	12
OESOPHAGUS	Regulation of organelle assembly →	+0.048	+0.714	.002	.002	3	12
SKIN	Thigmotaxis →	+0.284	+0.455	.008	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,551 associations by consensus.

Lipoprotein localization by GGN expression — BLOOD_Myeloma

Explore this box plot interactively →