GFM1

Across TCGA patient cohorts, GFM1 mutation is significantly associated with the RNA expression of many other genes, with 3,888 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GFM1-associated genes across cancer lineages are RNA5SP412, SNORD31B, and RN7SL248P. Each is linked with GFM1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GFM1-to-partner and partner-to-GFM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by GFM1-low versus GFM1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFM1→partner) and Y-score (partner→GFM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.492	+1.613	<.001	.005	3	3
BRCA	SNORD31B →	+0.613	+5.070	<.001	.008	3	3
UCEC	RN7SL248P →	+0.060	+3.289	<.001	<.001	3	2
LUAD	RNU6-695P →	+0.897	+4.074	<.001	.005	3	2
LUSC	AQP7P4 →	+0.033	+4.496	<.001	.007	3	2
LUSC	BRK1P1 →	+0.227	+3.715	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,888 associations by consensus.

RNA5SP412 by GFM1 expression — UCEC

Explore this box plot interactively →