GEMIN8P1

Across TCGA pan-cancer cohorts, GEMIN8P1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of GEMIN8P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where GEMIN8P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GEMIN8P1 is over-expressed in tumor, although a few such as LUSC and ESCA show the opposite, repressed pattern.

KIRC, BRCA, and PRAD are the cancer types where GEMIN8P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GEMIN8P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.039	<.001	7	view →
BRCA	All	All	+0.159	<.001	6	view →
PRAD	All	All	+0.141	<.001	2	view →
LIHC	All	All	+0.026	.011	2	view →
LUSC	Male	All	−0.022	.039	2	view →
ESCA	All	All	−0.061	.011	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

GEMIN8P1–KIRC

Open the KIRC breakdown →