GEMIN7

Across TCGA patient cohorts, GEMIN7 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,828 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GEMIN7-associated proteins across cancer lineages are PAFAH1B3, SMC3_S1074, and SRRT_S67. Each is linked with GEMIN7 in more than 4 cancer types. Because this analysis shows association rather than direction, both GEMIN7-to-partner and partner-to-GEMIN7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GEMIN7 versus PAFAH1B3 in BRCA, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GEMIN7→partner) and Y-score (partner→GEMIN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PAFAH1B3 →	+0.375	+0.382	<.001	<.001	3	5
HNSC	SMC3_S1074 →	+0.621	+0.510	<.001	.002	3	4
GBM	SRRT_S67 →	+0.411	+0.390	<.001	<.001	3	4
GBM	POLR2E →	+0.217	+0.288	<.001	<.001	3	4
GBM	ACIN1 →	+0.274	+0.339	<.001	<.001	3	4
HNSC	STRBP →	+0.545	+0.437	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,828 associations by consensus.

GEMIN7 vs PAFAH1B3 — BRCA

Explore this scatter interactively →