GDE1

Across TCGA patient cohorts, GDE1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,970 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GDE1-associated proteins across cancer lineages are ARFGEF3, COG7, and GSPT1. Each is linked with GDE1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GDE1-to-partner and partner-to-GDE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GDE1 versus ARFGEF3 in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GDE1→partner) and Y-score (partner→GDE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARFGEF3 →	+0.580	+0.703	<.001	<.001	3	5
BRCA	COG7 →	+0.201	+0.395	<.001	<.001	3	5
BRCA	GSPT1 →	+0.294	+0.501	<.001	.004	3	5
GBM	ABR →	+0.338	+0.261	<.001	.005	3	4
LUAD	PARN →	+0.237	+0.616	<.001	<.001	3	4
BRCA	KATNIP_S253 →	+0.476	+0.647	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,970 associations by consensus.

GDE1 vs ARFGEF3 — BRCA

Explore this scatter interactively →