GCSAML

Across TCGA patient cohorts, GCSAML RNA expression is significantly associated with the protein abundance of many other proteins, with 15,458 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GCSAML-associated proteins across cancer lineages are CPA3, SYTL3_S243, and TOP2A_S1525. Each is linked with GCSAML in more than 6 cancer types. Because this analysis shows association rather than direction, both GCSAML-to-partner and partner-to-GCSAML results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCSAML versus CPA3 in BRCA, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GCSAML→partner) and Y-score (partner→GCSAML) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CPA3 →	+1.161	+0.493	<.001	<.001	3	7
LSCC	SYTL3_S243 →	+0.822	+0.265	<.001	<.001	3	6
LSCC	TOP2A_S1525 →	-1.244	-0.230	<.001	.004	3	6
BRCA	VWA5A →	+0.524	+0.464	<.001	<.001	3	6
BRCA	HPGDS →	+0.681	+0.504	<.001	<.001	3	6
PDAC	NCAPG →	-0.465	-0.195	.005	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,458 associations by consensus.

GCSAML vs CPA3 — BRCA

Explore this scatter interactively →