GCG

Across TCGA patient cohorts, GCG RNA expression is significantly associated with the protein abundance of many other proteins, with 5,926 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GCG-associated proteins across cancer lineages are SRSF9_S204, ENG, and AKAP12_S627. Each is linked with GCG in more than 2 cancer types. Because this analysis shows association rather than direction, both GCG-to-partner and partner-to-GCG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCG versus SRSF9_S204 in OV, with a Pearson correlation of -0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GCG→partner) and Y-score (partner→GCG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SRSF9_S204 →	-0.768	-0.113	.002	<.001	3	3
UCEC	ENG →	+0.349	+0.413	<.001	.002	3	3
PDAC	AKAP12_S627 →	+0.752	+3.875	<.001	<.001	3	3
LSCC	WDHD1_S407 →	-0.502	-0.082	<.001	.009	3	3
LSCC	NOLC1_S508 →	-1.092	-0.115	.001	.009	3	2
LSCC	OGFOD1 →	-0.306	-0.128	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,926 associations by consensus.

GCG vs SRSF9_S204 — OV

Explore this scatter interactively →