GCG

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GCG protein abundance is significantly associated with the protein abundance of many other proteins, with 15,232 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GCG-associated proteins across cancer lineages are CHGA, CHGA_S142, and CHGA_S322. Each is linked with GCG in more than 1 cancer types. Because this analysis shows association rather than direction, both GCG-to-partner and partner-to-GCG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCG versus CHGA in PDAC, with a Pearson correlation of 0.67.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GCG→partner) and Y-score (partner→GCG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACCHGA →+0.932+1.366<.001<.00132
PDACCHGA_S142 →+1.607+1.378<.001<.00132
PDACCHGA_S322 →+1.077+1.127<.001<.00132
PDACCHGA_S333 →+1.566+1.223<.001<.00132
PDACCHGB_S130 →+0.594+0.957<.001<.00132
PDACCHGB_S335 →+1.071+0.784<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,232 associations by consensus.

GCG vs CHGA — PDAC

Per-sample scatter of GCG vs CHGA in PDAC (Pearson r = 0.67).

Explore this scatter interactively →

Exploration