GCC1

Across TCGA patient cohorts, GCC1 mutation is significantly associated with the RNA expression of many other genes, with 1,821 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GCC1-associated genes across cancer lineages are RNU6-903P, LINC00326, and ANKRD33B-AS1. Each is linked with GCC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GCC1-to-partner and partner-to-GCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-903P grouped by GCC1-low versus GCC1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCC1→partner) and Y-score (partner→GCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RNU6-903P →	+0.597	+5.039	<.001	.008	3	2
READ	LINC00326 →	+0.819	+5.421	<.001	.005	3	2
READ	ANKRD33B-AS1 →	+0.187	+6.681	<.001	<.001	3	2
READ	MIR1273H →	+0.431	+5.653	<.001	.003	3	2
READ	MIR7156 →	+0.915	+5.421	<.001	.005	3	2
UCEC	CENPU →	+0.639	+1.868	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,821 associations by consensus.

RNU6-903P by GCC1 expression — READ

Explore this box plot interactively →