GC

Across TCGA patient cohorts, GC protein abundance is significantly associated with the RNA expression of many other genes, with 13,984 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GC-associated genes across cancer lineages are DIPK2B, MMP19, and CD93. Each is linked with GC in more than 7 cancer types. Because this analysis shows association rather than direction, both GC-to-partner and partner-to-GC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GC versus DIPK2B in BRCA, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GC→partner) and Y-score (partner→GC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DIPK2B →	+0.872	+0.727	<.001	<.001	3	8
OV	MMP19 →	+1.117	+0.627	<.001	.001	3	7
GBM	CD93 →	+0.972	+0.786	<.001	<.001	3	7
BRCA	GNG11 →	+0.937	+0.690	<.001	<.001	3	7
OV	NGF →	+0.831	+0.796	.001	<.001	3	7
COAD	VEGFC →	+0.967	+0.982	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,984 associations by consensus.

GC vs DIPK2B — BRCA

Explore this scatter interactively →