GATC

Across TCGA cell cohorts, GATC RNA expression is significantly associated with the go_rna of many other GO terms, with 5,144 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GATC-associated GO terms across cancer lineages are Regulation of translational fidelity, Regulation of double-strand break repair via homologous recombination, and External encapsulating structure organization. Each is linked with GATC in more than 16 cancer types. Because this analysis shows association rather than direction, both GATC-to-partner and partner-to-GATC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translational fidelity grouped by GATC-low versus GATC-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GATC→partner) and Y-score (partner→GATC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of translational fidelity →	+0.102	+0.543	<.001	<.001	3	17
BONE	Regulation of double-strand break repair via homologous recombination →	+0.089	+0.604	<.001	<.001	3	14
BONE	External encapsulating structure organization →	-0.294	-0.859	<.001	<.001	3	14
BONE	Cell adhesion mediated by integrin →	-0.236	-0.676	<.001	<.001	3	14
SOFT_TISSUE	Extracellular matrix organization →	-0.189	-0.593	<.001	<.001	3	14
SOFT_TISSUE	Extracellular structure organization →	-0.190	-0.593	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,144 associations by consensus.

Regulation of translational fidelity by GATC expression — BONE

Explore this box plot interactively →