GATA1

Across TCGA patient cohorts, GATA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,156 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GATA1-associated GO terms across cancer lineages are Post-embryonic development, Semaphorin-plexin signaling pathway, and Regulation of actin filament organization. Each is linked with GATA1 in more than 24 cancer types. Because this analysis shows association rather than direction, both GATA1-to-partner and partner-to-GATA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-embryonic development grouped by GATA1-low versus GATA1-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GATA1→partner) and Y-score (partner→GATA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Post-embryonic development →	+0.064	+0.191	.001	<.001	3	24
SCLC	Semaphorin-plexin signaling pathway →	+0.075	+0.147	<.001	.008	3	24
SCLC	Regulation of actin filament organization →	+0.053	+0.190	<.001	.001	2	25
STAD	Negative regulation of intrinsic apoptotic signaling pathway →	+0.053	+0.160	<.001	<.001	3	24
THYM	Protein targeting to lysosome →	+0.049	+0.273	.001	<.001	3	24
STAD	Ensheathment of neurons →	+0.043	+0.163	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,156 associations by consensus.

Post-embryonic development by GATA1 expression — SCLC

Explore this box plot interactively →