GAS2L3

Across TCGA patient cohorts, GAS2L3 mutation is significantly associated with the RNA expression of many other genes, with 2,210 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GAS2L3-associated genes across cancer lineages are RN7SL248P, RPL21P9, and LINC02281. Each is linked with GAS2L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAS2L3-to-partner and partner-to-GAS2L3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by GAS2L3-low versus GAS2L3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAS2L3→partner) and Y-score (partner→GAS2L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.073	+3.330	<.001	<.001	3	2
SKCM	RPL21P9 →	+0.111	+3.331	<.001	.002	3	2
LIHC	LINC02281 →	+0.129	+5.647	<.001	.004	3	2
HNSC	RNU6-308P →	+0.398	+5.124	<.001	.008	3	2
LUAD	RNU6-138P →	+0.274	+4.418	<.001	.006	3	2
LUAD	RNU4-60P →	+0.365	+3.685	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,210 associations by consensus.

RN7SL248P by GAS2L3 expression — UCEC

Explore this box plot interactively →