GALNT8

Across TCGA cell cohorts, GALNT8 mutation is significantly associated with the RNA expression of many other genes, with 85 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GALNT8-associated genes across cancer lineages are OR1N2, GNGT1, and NXNL1. Each is linked with GALNT8 in more than 1 cancer types. Because this analysis shows association rather than direction, both GALNT8-to-partner and partner-to-GALNT8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1N2 grouped by GALNT8-low versus GALNT8-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALNT8→partner) and Y-score (partner→GALNT8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR1N2 →	+0.018	+3.700	<.001	.005	3	2
CNS	GNGT1 →	+1.815	+3.923	<.001	<.001	3	2
CNS	NXNL1 →	+0.984	+2.771	<.001	.003	3	2
BLOOD_Leukemia	ADAMTS18 →	+0.620	+3.091	<.001	.001	3	2
PANCREAS	OPRPN →	+0.018	+5.000	.001	.006	3	1
OESOPHAGUS	OR8B4 →	+0.036	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 85 associations by consensus.

OR1N2 by GALNT8 expression — OVARY

Explore this box plot interactively →