GALM

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GALM protein abundance is significantly associated with the RNA expression of many other genes, with 16,313 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GALM-associated genes across cancer lineages are CTSS, FBP1, and NR1H3. Each is linked with GALM in more than 6 cancer types. Because this analysis shows association rather than direction, both GALM-to-partner and partner-to-GALM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GALM versus CTSS in HNSC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GALM→partner) and Y-score (partner→GALM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCCTSS →+1.121+0.658<.001<.00137
LUADFBP1 →+1.012+0.448<.001<.00137
UCECNR1H3 →+0.696+0.428.003<.00137
HNSCCD96 →+1.033+0.548<.001<.00136
UCECTRAV8-2 →+0.735+0.428<.001.00136
GBMNCF4 →+0.943+0.510<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,313 associations by consensus.

GALM vs CTSS — HNSC

Per-sample scatter of GALM vs CTSS in HNSC (Pearson r = 0.34).

Explore this scatter interactively →

Exploration