GALM

Across TCGA cell cohorts, GALM RNA expression is significantly associated with the go_rna of many other GO terms, with 3,178 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GALM-associated GO terms across cancer lineages are Branched-chain amino acid catabolic process, Sulfur compound metabolic process, and Energy derivation by oxidation of organic compounds. Each is linked with GALM in more than 8 cancer types. Because this analysis shows association rather than direction, both GALM-to-partner and partner-to-GALM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Branched-chain amino acid catabolic process grouped by GALM-low versus GALM-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GALM→partner) and Y-score (partner→GALM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Branched-chain amino acid catabolic process →	+0.074	+1.583	<.001	<.001	2	9
LARGE_INTESTINE	Sulfur compound metabolic process →	+0.038	+0.720	<.001	.001	3	8
BLOOD_Lymphoma	Energy derivation by oxidation of organic compounds →	+0.057	+2.549	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Branched-chain amino acid metabolic process →	+0.064	+1.295	<.001	<.001	3	7
OVARY	Lysosomal transport →	+0.042	+1.251	.006	.002	3	7
OVARY	Positive regulation of phospholipid biosynthetic process →	+0.119	+1.542	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,178 associations by consensus.

Branched-chain amino acid catabolic process by GALM expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →