GADD45B

Across TCGA patient cohorts, GADD45B RNA expression is significantly associated with the protein abundance of many other proteins, with 18,161 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GADD45B-associated proteins across cancer lineages are ZYX_S344, LMNA_S423, and PRPF38B_S529. Each is linked with GADD45B in more than 8 cancer types. Because this analysis shows association rather than direction, both GADD45B-to-partner and partner-to-GADD45B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GADD45B versus ZYX_S344 in OV, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GADD45B→partner) and Y-score (partner→GADD45B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZYX_S344 →	+0.732	+0.738	.007	.005	3	9
LSCC	LMNA_S423 →	+1.111	+0.800	<.001	<.001	3	8
CCRCC	PRPF38B_S529 →	-0.487	-0.664	<.001	<.001	3	7
OV	PRR14_T363 →	+0.732	+0.725	<.001	<.001	3	7
BRCA	PLXDC2 →	+0.543	+0.759	.001	<.001	3	7
COAD	SERPING1 →	+0.500	+0.767	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,161 associations by consensus.

GADD45B vs ZYX_S344 — OV

Explore this scatter interactively →