GADD45B

Across TCGA patient cohorts, GADD45B protein abundance is significantly associated with the RNA expression of many other genes, with 338 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GADD45B-associated genes across cancer lineages are ERICH1, KCNA7, and HRG. Each is linked with GADD45B in more than 1 cancer types. Because this analysis shows association rather than direction, both GADD45B-to-partner and partner-to-GADD45B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GADD45B versus ERICH1 in GBM, with a Pearson correlation of 0.89.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GADD45B→partner) and Y-score (partner→GADD45B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ERICH1 →	+0.536	+0.925	.007	.007	3	1
GBM	KCNA7 →	+0.099	+0.925	<.001	.007	3	1
GBM	HRG →	+0.030	+0.924	.009	.007	3	1
GBM	NEURL2 →	+0.701	+1.323	.008	.004	3	1
GBM	CCDC138 →	+1.036	+0.925	.008	.007	3	1
GBM	OR13J1 →	+0.860	+1.393	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 338 associations by consensus.

GADD45B vs ERICH1 — GBM

Explore this scatter interactively →