GADD45B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GADD45B mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GADD45B-associated genes across cancer lineages are C8A. Each is linked with GADD45B in more than 1 cancer types. Because this analysis shows association rather than direction, both GADD45B-to-partner and partner-to-GADD45B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C8A grouped by GADD45B-low versus GADD45B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GADD45B→partner) and Y-score (partner→GADD45B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEC8A →+0.039+4.684<.001.00231
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

C8A by GADD45B expression — LARGE_INTESTINE

Box plot of C8A in GADD45B-low vs GADD45B-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration