GABRP

Across TCGA cell cohorts, GABRP mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GABRP-associated genes across cancer lineages are OOSP4B, CCL23, and EPB42. Each is linked with GABRP in more than 1 cancer types. Because this analysis shows association rather than direction, both GABRP-to-partner and partner-to-GABRP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OOSP4B grouped by GABRP-low versus GABRP-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRP→partner) and Y-score (partner→GABRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OOSP4B →	+0.040	+5.781	<.001	.001	3	1
BREAST	CCL23 →	+0.058	+5.169	<.001	.005	3	1
LUNG_NSCLC_LUAD	EPB42 →	+0.026	+4.734	<.001	.002	3	1
BLOOD_Leukemia	HAO1 →	+0.039	+4.276	<.001	.007	3	1
BLOOD_Leukemia	ZIC3 →	+0.019	+5.060	<.001	.001	3	1
BLOOD_Leukemia	CFHR2 →	+0.296	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OOSP4B by GABRP expression — BREAST

Explore this box plot interactively →