GABRP

Across TCGA pan-cancer cohorts, GABRP RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of GABRP’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where GABRP RNA is repressed in tumor relative to normal tissue. In most cancer types GABRP is over-expressed in tumor, although a few such as HNSC and KICH show the opposite, repressed pattern.

HNSC, KICH, and KIRC are the cancer types where GABRP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GABRP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	II,III,IV	−3.447	<.001	11	view →
KICH	Female	All	−2.694	<.001	11	view →
KIRC	Male	II,III,IV	−2.166	<.001	11	view →
COAD	Female	II,III,IV	+1.622	<.001	7	view →
BRCA	All	III,IV	−3.378	<.001	6	view →
LIHC	Male	All	−0.861	<.001	5	view →
KIRP	Male	All	−1.403	<.001	4	view →
STAD	Female	III,IV	+5.975	.007	3	view →
LUSC	Male	All	+1.380	<.001	2	view →
READ	All	All	+1.171	.033	2	view →
PRAD	All	All	−0.829	.010	2	view →
LUAD	All	All	+0.549	.043	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

GABRP–HNSC

Open the HNSC breakdown →