GABRA6

Across TCGA cell cohorts, GABRA6 RNA expression is significantly associated with the mutation status of many other genes, with 96 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GABRA6-associated genes across cancer lineages are GNPTAB, ZBTB11, and ARHGAP21. Each is linked with GABRA6 in more than 1 cancer types. Because this analysis shows association rather than direction, both GABRA6-to-partner and partner-to-GABRA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GNPTAB grouped by GABRA6-low versus GABRA6-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRA6→partner) and Y-score (partner→GABRA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	GNPTAB →	+3.870	+0.047	.003	<.001	3	2
SKIN	ZBTB11 →	+3.684	+0.103	.006	<.001	3	2
LUNG_NSCLC_LUAD	ARHGAP21 →	+3.189	+0.046	.007	<.001	3	2
LUNG_NSCLC_LUAD	PRRC2C →	+2.604	+0.032	.004	<.001	3	2
LUNG_NSCLC_LUAD	MOV10 →	+4.189	+0.066	.002	<.001	3	2
LUNG_NSCLC_LUAD	ZNF292 →	+2.282	+0.027	.007	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 96 associations by consensus.

GNPTAB by GABRA6 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →