GABRA4

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GABRA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,040 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GABRA4-associated proteins across cancer lineages are TSHZ1_T852, CHDH, and RCN1. Each is linked with GABRA4 in more than 2 cancer types. Because this analysis shows association rather than direction, both GABRA4-to-partner and partner-to-GABRA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GABRA4 versus TSHZ1_T852 in GBM, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRA4→partner) and Y-score (partner→GABRA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMTSHZ1_T852 →+0.470+0.903<.001<.00133
GBMCHDH →+0.333+0.958.005<.00133
GBMRCN1 →-0.368-0.733<.001<.00133
GBMSEPTIN4_S107 →+0.925+0.979.004.00133
GBMSEPTIN4_S117 →+0.758+0.798.003.00333
GBMCRMP1 →+0.553+1.018<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,040 associations by consensus.

GABRA4 vs TSHZ1_T852 — GBM

Per-sample scatter of GABRA4 vs TSHZ1_T852 in GBM (Pearson r = 0.36).

Explore this scatter interactively →

Exploration