GABRA4

Across TCGA cell cohorts, GABRA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 192 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GABRA4-associated GO terms across cancer lineages are Positive regulation of exosomal secretion, Actomyosin contractile ring assembly actin filament organization, and Cytoplasm protein quality control. Each is linked with GABRA4 in more than 2 cancer types. Because this analysis shows association rather than direction, both GABRA4-to-partner and partner-to-GABRA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of exosomal secretion grouped by GABRA4-low versus GABRA4-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GABRA4→partner) and Y-score (partner→GABRA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of exosomal secretion →	-0.074	-0.555	<.001	.008	3	3
LUNG_SCLC	Actomyosin contractile ring assembly actin filament organization →	-0.187	-0.207	<.001	.008	3	3
BLOOD_Leukemia	Cytoplasm protein quality control →	+0.057	+0.615	.002	.007	2	3
BLOOD_Leukemia	Positive regulation of odontoblast differentiation →	-0.155	-0.578	<.001	.006	3	2
BLOOD_Leukemia	Positive regulation of neuroepithelial cell differentiation →	-0.155	-0.578	<.001	.006	3	2
BLOOD_Leukemia	Regulation of glutamate secretion, neurotransmission →	-0.076	-0.602	.004	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 192 associations by consensus.

Positive regulation of exosomal secretion by GABRA4 expression — BLOOD_Leukemia

Explore this box plot interactively →