FZD1

Across TCGA patient cohorts, FZD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,333 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FZD1-associated proteins across cancer lineages are SH3PXD2B, ITGB5, and RAI14. Each is linked with FZD1 in more than 7 cancer types. Because this analysis shows association rather than direction, both FZD1-to-partner and partner-to-FZD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FZD1 versus SH3PXD2B in OV, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FZD1→partner) and Y-score (partner→FZD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SH3PXD2B →	+0.412	+0.812	<.001	<.001	3	8
LSCC	ITGB5 →	+0.624	+0.974	<.001	<.001	3	8
BRCA	RAI14 →	+0.393	+0.938	<.001	<.001	3	8
BRCA	PPFIBP1 →	+0.393	+0.939	<.001	<.001	3	7
OV	SEPTIN11 →	+0.400	+0.959	<.001	<.001	3	7
BRCA	CD38 →	-0.763	-0.684	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,333 associations by consensus.

FZD1 vs SH3PXD2B — OV

Explore this scatter interactively →