FYN

Across TCGA patient cohorts, FYN RNA expression is significantly associated with the protein abundance of many other proteins, with 19,541 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FYN-associated proteins across cancer lineages are RASA3, TBC1D2B, and FYN_S21. Each is linked with FYN in more than 7 cancer types. Because this analysis shows association rather than direction, both FYN-to-partner and partner-to-FYN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FYN versus RASA3 in HNSC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FYN→partner) and Y-score (partner→FYN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RASA3 →	+0.299	+0.763	<.001	<.001	3	8
UCEC	TBC1D2B →	+0.265	+0.664	<.001	<.001	3	8
UCEC	FYN_S21 →	+1.144	+1.382	<.001	<.001	3	8
LUAD	MRPL47 →	-0.379	-0.671	<.001	<.001	3	8
BRCA	MRPS5 →	-0.355	-0.616	<.001	<.001	3	8
UCEC	PPP1R9B →	+0.249	+0.800	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,541 associations by consensus.

FYN vs RASA3 — HNSC

Explore this scatter interactively →