FUT3

Across TCGA patient cohorts, FUT3 mutation is significantly associated with the RNA expression of many other genes, with 2,953 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FUT3-associated genes across cancer lineages are RPL5P31, CCNYL3, and SNHG21. Each is linked with FUT3 in more than 2 cancer types. Because this analysis shows association rather than direction, both FUT3-to-partner and partner-to-FUT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL5P31 grouped by FUT3-low versus FUT3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FUT3→partner) and Y-score (partner→FUT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RPL5P31 →	+0.121	+4.064	<.001	.004	3	3
THCA	CCNYL3 →	+0.029	+7.962	<.001	.007	3	2
SKCM	SNHG21 →	+0.503	+2.057	.004	.005	3	2
SKCM	RTN3P1 →	+0.280	+2.681	<.001	.004	3	2
SKCM	PAICSP4 →	+0.253	+2.572	<.001	<.001	3	2
SKCM	RCCD1-AS1 →	+0.236	+3.265	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,953 associations by consensus.

RPL5P31 by FUT3 expression — BLCA

Explore this box plot interactively →