ferritin heavy chain 1 pseudogene 21Genealiases: FTHL21 · FTHP2
Q-omics provides the consensus-scored FTH1P21 profile across patient tissues and cancer cell-line models. FTH1P21 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in SKCM. Among the 18 cancer types available for tumor–normal comparison, FTH1P21 is differentially expressed in 7, with the highest sampling consensus in UCEC. Additionally, FTH1P21 RNA expression shows 6,131 significant pathway-activity associations, with the highest sampling consensus in LGG. Together, these results highlight SKCM, UCEC, and LGG as cancer lineages where FTH1P21 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for FTH1P21 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes FTH1P21 survival associations across molecular data types. FTH1P21 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible FTH1P21 RNA expression–survival associations across cancer types. High FTH1P21 expression shows unfavorable associations in KICH and STAD, but favorable associations in SKCM, LUAD, ESCA and MESO. The SKCM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for FTH1P21 RNA expression.
This table summarizes FTH1P21 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in UCEC for RNA.
This table ranks reproducible tumor–normal expression differences for FTH1P21. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. FTH1P21 shows lower tumor expression in STAD and higher tumor expression in UCEC, KICH, LIHC, KIRC and HNSC. The UCEC box plot shows higher FTH1P21 RNA expression in tumor versus normal tissue (log2 FC = +0.200, t-test p < 0.001).
This table shows molecular features associated with FTH1P21 in patient tissues and cancer cell lines. In patient samples, FTH1P21 shows the broadest associations at the RNA and protein expression levels, with LGG recurring as the lineage with the largest associated feature set.
