FTH1P21

Across TCGA pan-cancer cohorts, FTH1P21 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of FTH1P21’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where FTH1P21 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FTH1P21 is over-expressed in tumor, although a few such as STAD and READ show the opposite, repressed pattern.

UCEC, KICH, and LIHC are the cancer types where FTH1P21 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FTH1P21 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	+0.200	<.001	6	view →
KICH	Female	All	+0.108	<.001	5	view →
LIHC	Male	All	+0.058	.002	5	view →
KIRC	All	All	+0.064	.008	4	view →
HNSC	All	II,III,IV	+0.085	.028	3	view →
STAD	All	IV	−0.213	.007	2	view →
READ	All	All	−0.115	.024	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

FTH1P21–UCEC

Open the UCEC breakdown →