FSHB

Across TCGA patient cohorts, FSHB mutation is significantly associated with the RNA expression of many other genes, with 404 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible FSHB-associated genes across cancer lineages are TAF11L14, RPL5P19, and LINC00351. Each is linked with FSHB in more than 1 cancer types. Because this analysis shows association rather than direction, both FSHB-to-partner and partner-to-FSHB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAF11L14 grouped by FSHB-low versus FSHB-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSHB→partner) and Y-score (partner→FSHB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TAF11L14 →	+1.501	+5.010	<.001	.009	3	2
CESC	RPL5P19 →	+0.060	+6.144	<.001	.001	3	2
CESC	LINC00351 →	+0.084	+5.201	.002	.007	3	2
COAD	OR5D3P →	+0.084	+5.917	<.001	.001	3	2
COAD	ARF1P1 →	+0.356	+4.324	.004	.007	3	2
LUSC	RNU6-796P →	+0.586	+5.548	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 404 associations by consensus.

TAF11L14 by FSHB expression — CESC

Explore this box plot interactively →