FSHB

Across TCGA cell cohorts, FSHB RNA expression is significantly associated with the mutation status of many other genes, with 180 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FSHB-associated genes across cancer lineages are SOX4, ADCY8, and CACNA1D. Each is linked with FSHB in more than 1 cancer types. Because this analysis shows association rather than direction, both FSHB-to-partner and partner-to-FSHB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SOX4 grouped by FSHB-low versus FSHB-high in BLOOD_Lymphoma.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FSHB→partner) and Y-score (partner→FSHB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SOX4 →	+5.247	+0.012	.001	<.001	3	2
BLOOD_Lymphoma	ADCY8 →	+4.662	+0.010	.003	<.001	3	2
BLOOD_Lymphoma	CACNA1D →	+4.247	+0.008	.004	<.001	3	2
BLOOD_Lymphoma	MAP3K2 →	+3.925	+0.007	.006	<.001	3	2
CNS	PATZ1 →	+5.321	+0.032	.005	<.001	3	2
CNS	NAA15 →	+5.321	+0.032	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 180 associations by consensus.

SOX4 by FSHB expression — BLOOD_Lymphoma

Explore this box plot interactively →