FRRS1

Across TCGA cell cohorts, FRRS1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FRRS1-associated genes across cancer lineages are MYH1, UGT2B28, and TGIF2LX. Each is linked with FRRS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FRRS1-to-partner and partner-to-FRRS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH1 grouped by FRRS1-low versus FRRS1-high in KIDNEY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRRS1→partner) and Y-score (partner→FRRS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	MYH1 →	+0.050	+5.000	<.001	.005	3	1
KIDNEY	UGT2B28 →	+0.013	+5.000	<.001	.005	3	1
KIDNEY	TGIF2LX →	+0.053	+5.000	<.001	.005	3	1
KIDNEY	POTEM →	+0.069	+5.000	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR5H8 →	+0.022	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	USP17L18 →	+0.006	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

MYH1 by FRRS1 expression — KIDNEY

Explore this box plot interactively →