FRMPD3

Across TCGA cell cohorts, FRMPD3 mutation is significantly associated with the RNA expression of many other genes, with 621 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FRMPD3-associated genes across cancer lineages are SCGB1D2, CYP2C9, and ASB17. Each is linked with FRMPD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FRMPD3-to-partner and partner-to-FRMPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB1D2 grouped by FRMPD3-low versus FRMPD3-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMPD3→partner) and Y-score (partner→FRMPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SCGB1D2 →	+0.965	+3.657	<.001	.006	3	2
LUNG_SCLC	CYP2C9 →	+0.343	+3.617	<.001	.004	3	2
CNS	ASB17 →	+0.011	+4.357	<.001	.004	3	2
LARGE_INTESTINE	CHP1 →	+0.565	+2.829	.002	<.001	3	2
LUNG_SCLC	OR14K1 →	+0.098	+4.006	<.001	<.001	3	2
LUNG_SCLC	OR1C1 →	+0.031	+3.353	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 621 associations by consensus.

SCGB1D2 by FRMPD3 expression — CNS

Explore this box plot interactively →