FRMD4B

Across TCGA patient cohorts, FRMD4B protein abundance is significantly associated with the RNA expression of many other genes, with 5,220 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FRMD4B-associated genes across cancer lineages are GSTO1, PLCB1, and RPL7AP4. Each is linked with FRMD4B in more than 2 cancer types. Because this analysis shows association rather than direction, both FRMD4B-to-partner and partner-to-FRMD4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FRMD4B versus GSTO1 in LSCC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FRMD4B→partner) and Y-score (partner→FRMD4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GSTO1 →	+0.507	+0.273	.005	.001	3	3
HNSC	PLCB1 →	-0.985	-0.590	.009	.009	3	2
GBM	RPL7AP4 →	-0.548	-0.445	.003	.004	3	2
UCEC	PLCB1-IT1 →	-1.696	-0.394	.003	.004	3	2
HNSC	MIR6129 →	-1.367	-0.614	.003	.001	3	2
CCRCC	PAX4 →	+0.033	+0.283	.007	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,220 associations by consensus.

FRMD4B vs GSTO1 — LSCC

Explore this scatter interactively →