FOXN1

Across TCGA patient cohorts, FOXN1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,358 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FOXN1-associated genes across cancer lineages are SH2B3, PECR, and ZNF45. Each is linked with FOXN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FOXN1-to-partner and partner-to-FOXN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXN1 versus SH2B3 in HNSC, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXN1→partner) and Y-score (partner→FOXN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SH2B3 →	+0.764	+0.447	.003	.001	3	3
LUAD	PECR →	+0.447	+0.373	.001	<.001	3	2
PDAC	ZNF45 →	+0.399	+0.493	.003	.005	3	2
LUAD	ZNF546 →	+0.339	+0.376	<.001	<.001	3	2
PDAC	RNVU1-3 →	+0.659	+0.477	<.001	<.001	3	2
PDAC	RNU6-450P →	+0.732	+0.364	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,358 associations by consensus.

FOXN1 vs SH2B3 — HNSC

Explore this scatter interactively →