FOXL2NB

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FOXL2NB mutation is significantly associated with the RNA expression of many other genes, with 149 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXL2NB-associated genes across cancer lineages are TRIM64DP, MIR4529, and FRG2MP. Each is linked with FOXL2NB in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXL2NB-to-partner and partner-to-FOXL2NB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXL2NB→partner) and Y-score (partner→FOXL2NB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMTRIM64DP →+0.051+4.475<.001.00532
SKCMMIR4529 →+0.274+5.163<.001.00232
SKCMFRG2MP →+0.031+4.147<.001.00832
SKCMHIGD1AP4 →+0.896+4.152<.001.00132
UCECRNU6-618P →+0.477+3.384<.001<.00132
UCECRNA5SP167 →+0.476+4.245<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 149 associations by consensus.

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