FSHD region gene 2 family member M, pseudogeneGenealiases: []
Q-omics provides the consensus-scored FRG2MP profile across patient tissues and cancer cell-line models. FRG2MP expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, FRG2MP is differentially expressed in 1, with the highest sampling consensus in STAD. Additionally, FRG2MP RNA expression shows 6,693 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight KICH, STAD, and COAD as cancer lineages where FRG2MP shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for FRG2MP — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes FRG2MP survival associations across molecular data types. FRG2MP RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible FRG2MP RNA expression–survival associations across cancer types. High FRG2MP expression shows unfavorable associations in KICH, TGCT, COAD, LIHC and PAAD, but favorable associations in STAD. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for FRG2MP RNA expression.
This table summarizes FRG2MP tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in STAD for RNA.
This table ranks reproducible tumor–normal expression differences for FRG2MP. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. FRG2MP shows lower tumor expression in STAD. The STAD box plot shows higher FRG2MP RNA expression in normal versus tumor tissue (log2 FC = −0.023, t-test p = .040).
This table shows molecular features associated with FRG2MP in patient tissues and cancer cell lines. In patient samples, FRG2MP shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.
