FOXJ1

Across TCGA cell cohorts, FOXJ1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FOXJ1-associated genes across cancer lineages are PAGE4, RNF113B, and SSX3. Each is linked with FOXJ1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXJ1-to-partner and partner-to-FOXJ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PAGE4 grouped by FOXJ1-low versus FOXJ1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXJ1→partner) and Y-score (partner→FOXJ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PAGE4 →	+0.644	+3.339	<.001	.006	3	1
BLOOD_Leukemia	RNF113B →	+0.077	+3.450	<.001	.004	3	1
BLOOD_Leukemia	SSX3 →	+1.072	+3.824	<.001	.001	3	1
BLOOD_Leukemia	PRND →	+0.007	+3.289	<.001	.009	3	1
BLOOD_Leukemia	VSTM2B →	+0.069	+3.289	<.001	.009	3	1
BLOOD_Leukemia	CCT8L2 →	+0.009	+3.289	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

PAGE4 by FOXJ1 expression — BLOOD_Leukemia

Explore this box plot interactively →