Across TCGA patient cohorts, FOXI3 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXI3-associated genes across cancer lineages are MIR6864, MIR6807, and MIR6779. Each is linked with FOXI3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXI3-to-partner and partner-to-FOXI3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXI3→partner) and Y-score (partner→FOXI3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6864 →	+0.606	+2.739	.009	.006	3	1
UCEC	MIR6807 →	+0.743	+3.509	.006	.004	3	1
UCEC	MIR6779 →	+0.397	+3.420	<.001	.005	3	1
CESC	RNA5SP210 →	+0.630	+5.103	<.001	.008	3	1
CESC	MED15P3 →	+0.132	+5.969	<.001	.002	3	1
CESC	MIR8070 →	+0.701	+5.103	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

FOXI3 survival (RNA) · tumor vs normal (RNA) · all FOXI3 data types