Q-omics provides the consensus-scored MED15P3 profile across patient tissues and cancer cell-line models. MED15P3 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, MED15P3 is differentially expressed in 1, with the highest sampling consensus in KIRC. Additionally, MED15P3 RNA expression shows 6,879 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight COAD, KIRC, and THYM as cancer lineages where MED15P3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MED15P3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MED15P3 survival associations across molecular data types. MED15P3 RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MED15P3 RNA expression–survival associations across cancer types. High MED15P3 expression shows unfavorable associations in COAD, ESCA, HNSC, DLBC and THYM, but favorable associations in KIRC. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for MED15P3 RNA expression.
This table summarizes MED15P3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for MED15P3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MED15P3 shows higher tumor expression in KIRC. The KIRC box plot shows higher MED15P3 RNA expression in tumor versus normal tissue (log2 FC = +0.018, t-test p = .045).
This table shows molecular features associated with MED15P3 in patient tissues and cancer cell lines. In patient samples, MED15P3 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
