Across TCGA pan-cancer cohorts, MED15P3 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MED15P3’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MED15P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MED15P3 is over-expressed in tumor.
KIRC are the cancer types where MED15P3 tumor–normal differential expression is most reproducible.