FOXA2

Across TCGA patient cohorts, FOXA2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,360 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FOXA2-associated genes across cancer lineages are LINC00261, WASF1, and ST6GALNAC5. Each is linked with FOXA2 in more than 3 cancer types. Because this analysis shows association rather than direction, both FOXA2-to-partner and partner-to-FOXA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXA2 versus LINC00261 in UCEC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXA2→partner) and Y-score (partner→FOXA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC00261 →	+1.684	+0.509	<.001	<.001	3	4
UCEC	WASF1 →	-0.953	-0.609	<.001	<.001	3	3
UCEC	ST6GALNAC5 →	-1.028	-0.608	<.001	<.001	3	3
UCEC	ATP5IF1 →	+0.488	+0.415	.001	.001	3	3
PDAC	ATP1A1 →	+0.742	+0.526	<.001	<.001	3	3
UCEC	CLMP →	-0.667	-0.457	.009	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,360 associations by consensus.

FOXA2 vs LINC00261 — UCEC

Explore this scatter interactively →