FOLH1B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FOLH1B mutation is significantly associated with the RNA expression of many other genes, with 3,555 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOLH1B-associated genes across cancer lineages are MIR6803, EMC3-AS1, and CDKN3. Each is linked with FOLH1B in more than 2 cancer types. Because this analysis shows association rather than direction, both FOLH1B-to-partner and partner-to-FOLH1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by FOLH1B-low versus FOLH1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOLH1B→partner) and Y-score (partner→FOLH1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR6803 →+0.094+3.723<.001.00833
UCECEMC3-AS1 →+0.375+2.178.007.00133
UCECCDKN3 →+0.708+2.273<.001<.00133
UCECZC3H14 →+0.393+1.673<.001.00333
UCECMTPN →+0.566+1.971<.001.00733
UCECRPA3 →+0.481+2.273<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,555 associations by consensus.

MIR6803 by FOLH1B expression — UCEC

Box plot of MIR6803 in FOLH1B-low vs FOLH1B-high samples in UCEC.

Explore this box plot interactively →

Exploration