FOLH1B

Across TCGA pan-cancer cohorts, FOLH1B RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated FOLH1B data layer compared with 8 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FOLH1B RNA is associated with better overall survival. In most high-consensus cancer types, elevated FOLH1B expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCEC show a favorable association.

KIRC, STAD, and UCEC are the cancer types where FOLH1B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.848	0.763	<.001	112	view →
STAD	OS	Median	III,IV	0.265	0.696	<.001	76	view →
UCEC	OS	Tertile	IV	0.786	0.257	.002	64	view →
THYM	OS	Tertile	All	0.692	1.000	<.001	51	view →
LIHC	DFS	Median	All	0.525	0.363	.002	43	view →
COAD	OS	Median	IV	0.229	0.701	<.001	41	view →
LAML	DFS	Tertile	All	0.720	0.308	.008	30	view →
BLCA	DFS	Quartile	IV	0.260	0.512	<.001	23	view →
SARC	DFS	Quartile	All	0.528	0.680	.008	12	view →
CHOL	DFS	Tertile	II,III,IV	0.098	0.482	.017	12	view →
SKCM	OS	Tertile	All	0.393	0.291	.028	11	view →
CESC	OS	Median	II,III,IV	0.669	0.298	.026	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

FOLH1B–KIRC (OS)

Open the KIRC breakdown →