FOLH1B

Across TCGA patient cohorts, FOLH1B mutation is significantly associated with the total protein of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOLH1B-associated genes across cancer lineages are FoxM1, Cyclin-E2, and Collagen-VI. Each is linked with FOLH1B in more than 3 cancer types. Because this analysis shows association rather than direction, both FOLH1B-to-partner and partner-to-FOLH1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by FOLH1B-low versus FOLH1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOLH1B→partner) and Y-score (partner→FOLH1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.249	+2.070	.005	.001	3	4
COAD	Cyclin-E2 →	+0.787	+2.832	<.001	.034	3	4
LUSC	Collagen-VI →	-0.326	-3.450	.014	.005	3	3
COAD	TFRC →	+0.628	+3.025	.022	.019	3	3
UCEC	ASNS →	+0.323	+2.321	.009	.005	3	3
COAD	ATM →	-0.738	-2.991	<.001	.036	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

FoxM1 by FOLH1B expression — UCEC

Explore this box plot interactively →