FOLH1

Across TCGA patient cohorts, FOLH1 mutation is significantly associated with the RNA expression of many other genes, with 4,002 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOLH1-associated genes across cancer lineages are DCPS, SLC25A39, and FANCG. Each is linked with FOLH1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FOLH1-to-partner and partner-to-FOLH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCPS grouped by FOLH1-low versus FOLH1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOLH1→partner) and Y-score (partner→FOLH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DCPS →	+0.577	+3.333	<.001	.005	3	4
UCEC	SLC25A39 →	+0.264	+2.103	.007	.003	3	4
UCEC	FANCG →	+0.539	+2.294	<.001	<.001	3	4
UCEC	TK1 →	+0.425	+1.551	.009	.002	3	4
UCEC	TYMSOS →	+0.763	+2.305	<.001	<.001	3	4
LUAD	WDR62 →	+0.789	+2.620	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,002 associations by consensus.

DCPS by FOLH1 expression — LUAD

Explore this box plot interactively →