FNDC3B

Across TCGA cell cohorts, FNDC3B RNA expression is significantly associated with the go_rna of many other GO terms, with 6,629 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FNDC3B-associated GO terms across cancer lineages are Protein targeting to membrane, Viral process, and Endoplasmic reticulum to cytosol transport. Each is linked with FNDC3B in more than 16 cancer types. Because this analysis shows association rather than direction, both FNDC3B-to-partner and partner-to-FNDC3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein targeting to membrane grouped by FNDC3B-low versus FNDC3B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC3B→partner) and Y-score (partner→FNDC3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein targeting to membrane →	+0.105	+1.344	<.001	<.001	3	17
BONE	Viral process →	+0.087	+1.585	<.001	<.001	3	17
OESOPHAGUS	Endoplasmic reticulum to cytosol transport →	+0.183	+1.248	.002	<.001	3	17
OESOPHAGUS	Retrograde protein transport, ER to cytosol →	+0.183	+1.248	.002	<.001	3	17
OESOPHAGUS	Protein exit from endoplasmic reticulum →	+0.172	+1.112	.002	.003	3	17
BONE	Response to endoplasmic reticulum stress →	+0.098	+2.139	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,629 associations by consensus.

Protein targeting to membrane by FNDC3B expression — STOMACH

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