FNBP4

Across TCGA cell cohorts, FNBP4 mutation is significantly associated with the RNA expression of many other genes, with 1,227 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FNBP4-associated genes across cancer lineages are OR2C1, OR1N2, and R3HDML. Each is linked with FNBP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FNBP4-to-partner and partner-to-FNBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2C1 grouped by FNBP4-low versus FNBP4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNBP4→partner) and Y-score (partner→FNBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR2C1 →	+0.063	+1.948	.005	.006	3	2
LUNG_SCLC	OR1N2 →	+0.025	+5.029	<.001	.006	3	1
BLOOD_Lymphoma	R3HDML →	+0.006	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	BANF2 →	+0.047	+5.643	<.001	.002	3	1
LARGE_INTESTINE	PES1 →	+0.497	+4.122	.002	<.001	3	1
LARGE_INTESTINE	TFIP11 →	+0.375	+2.850	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,227 associations by consensus.

OR2C1 by FNBP4 expression — LARGE_INTESTINE

Explore this box plot interactively →